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Nolvadex - Drug Description
The first big advance in the fight against recurrent breast cancer was the drug tamoxifen (Nolvadex). In September 1998 a major study demonstrated that breast cancer recurrence could be reduced with tamoxifen.  Within one month the FDA had approved the drug. During the intervening years the data have been remarkably consistent: taking tamoxifen for 5 years post diagnosis reduces a woman's risk of estrogen receptor (ER)-positive breast cancer recurrence by about 50%. The big unanswered question, however, has been how long should a woman continue to take this drug. Until this week the answer has been 5 years.  But new and compelling data suggest that 10 years might be a better target. The study was published in The Lancet (Dec. 5, 2012).  Researchers followed nearly 13,000 women who had ER-positive breast cancer for 15 years. One group of women took tamoxifen for five years and then were switched to placebo.  ... click here to more information.

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